Rheumatologists have extensive experience using biologic agents which suppress inflammation. White blood cells talk a lot sending signals (cytokines) to other cells which can turn inflammation on and off. This language may be critical in Covid19 infections for good and bad. Medicines which suppress inflammation may be vital in preventing lung and heart damage from Covid19. However, too much suppression of inflammation can allow infections to develop. The following article in the Philadelphia Inquirer outlines a Covid19 patient who appears to have responded to a medication normally used for rheumatoid arthritis, Actemra. It suppresses a cytokine known as interleukin 6. We don't know yet if Actemra is beneficial for treating Covid19 or if the risk of infection outweighs the benefit. More recent studies suggest that another family of cytokine inhibitors of interleukin 1, Kineret and Ilaris, may be helpful in treating Covid19. These drugs are also used in rheumatoid arthritis and are not as yet approved for use in Covid19 infections. Nevertheless, until a vaccine is available, research may provide other ways to help control this plague. In the meantime, continue to social distance, wear your mask and wash hands. ... See MoreSee Less
3 weeks ago
